
Shingles & Postherpetic Neuralgia (PHN)
Shingles
Treatment
Prodrome: Burning pain, headache, fever, lymphadenopathy
Antivirals (if within 72 hrs of rash onset): Valaciclovir 1 g TDS x 7 days
Start anytime if immunocompromised or ophthalmic involvement
Consider Prednisolone 50 mg OD x 7 days (severe cases)
Symptomatic relief: Ice packs, paracetamol
Early antiviral therapy ↓ PHN risk
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Postherpetic Neuralgia (PHN)
Persistent pain >3 months post-infection (rare if <50 yrs)
Zostavax reduces risk in older adults
Management
First-line: Lignocaine 5% patch (localised pain)
Systemic first-line: Amitriptyline 10 mg nocte, titrate as needed
Second-line: Pregabalin 75 mg OD or Gabapentin 100 mg BD (adjust per response)
Adjuvants: Paracetamol, ice massage, Duloxetine if needed
Refractory cases: TENS (2 weeks), Tramadol 100 mg daily, opioids
CBT for chronic pain & mood disturbances
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Vaccination Against Shingles & PHN
Recommended ≥60 yrs (funded 70–79 yrs)
Household contacts ≥50 yrs (if living with immunocompromised patients)
Give before an outbreak, NOT during active shingles
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Contraindications
Pregnancy or ≤4 weeks postpartum
Shingles within past year (temporary immunity)
Immunocompromised (live vaccine risk)
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Notes
Antiepileptics & topical steroids ineffective for shingles/PHN
Same management principles apply to Ramsay Hunt syndrome
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