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Cardiovascular

Contact Dermatitis



Definition

  • Inflammation of the skin following exposure to an irritant or allergen

  • Two main types:

    • Allergic contact dermatitis (ACD) → Delayed hypersensitivity reaction

    • Irritant contact dermatitis (ICD) → Direct skin damage from irritants



Aetiology & Causes

Type

Mechanism

Common Triggers

Allergic Contact Dermatitis (ACD)

Immune-mediated (Type IV hypersensitivity)

Perfumes, plants, nickel, plaster, cosmetics

Irritant Contact Dermatitis (ICD)

Direct skin irritation from repetitive exposure

Detergents, soaps, excessive washing, chemicals

  • ACD: Can develop even if previously tolerated, triggered by small amounts

  • ICD: More common, particularly in people with atopic eczema


Symptoms

Feature

Allergic Contact Dermatitis

Irritant Contact Dermatitis

Location

Anywhere, commonly hands

Primarily hands

Appearance

Erythema, vesicles, bullae, well-demarcated

Dry, cracked skin, no blistering

Main Complaint

Itching

Burning & pain


Diagnosis

  • Usage Test: Apply suspected allergen to cubital fossa morning & night for up to 7 days

  • Patch Testing if the cause is unclear


Management


General Measures

  • Identify & avoid triggers

  • Use soap-free washes & emollients


Pharmacological Treatment

  • Topical steroids: Betamethasone dipropionate 0.05% OD until clear (max 4 weeks)

  • Oral corticosteroids: Prednisolone 25–50 mg for 1 week, then taper over 2 weeks (prevents rebound)

  • Oral antihistamines: For itch relief (e.g. cetirizine, loratadine)


Notes:

  • Irritant = more common, hands, burning, no vesicles

  • Allergic = distinct borders, vesicles/bullae, severe itching

  • Avoid triggers + use soap-free washes & emollients

  • Topical steroids (betamethasone 0.05%) = 1st-line

  • Oral steroids if severe (short course, taper to prevent rebound)

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