
Contact Dermatitis
Definition
Inflammation of the skin following exposure to an irritant or allergen
Two main types:
Allergic contact dermatitis (ACD) → Delayed hypersensitivity reaction
Irritant contact dermatitis (ICD) → Direct skin damage from irritants

Aetiology & Causes
Type | Mechanism | Common Triggers |
Allergic Contact Dermatitis (ACD) | Immune-mediated (Type IV hypersensitivity) | Perfumes, plants, nickel, plaster, cosmetics |
Irritant Contact Dermatitis (ICD) | Direct skin irritation from repetitive exposure | Detergents, soaps, excessive washing, chemicals |
ACD: Can develop even if previously tolerated, triggered by small amounts
ICD: More common, particularly in people with atopic eczema
Symptoms
Feature | Allergic Contact Dermatitis | Irritant Contact Dermatitis |
Location | Anywhere, commonly hands | Primarily hands |
Appearance | Erythema, vesicles, bullae, well-demarcated | Dry, cracked skin, no blistering |
Main Complaint | Itching | Burning & pain |
Diagnosis
Usage Test: Apply suspected allergen to cubital fossa morning & night for up to 7 days
Patch Testing if the cause is unclear
Management
General Measures
Identify & avoid triggers
Use soap-free washes & emollients
Pharmacological Treatment
Topical steroids: Betamethasone dipropionate 0.05% OD until clear (max 4 weeks)
Oral corticosteroids: Prednisolone 25–50 mg for 1 week, then taper over 2 weeks (prevents rebound)
Oral antihistamines: For itch relief (e.g. cetirizine, loratadine)
Notes:
Irritant = more common, hands, burning, no vesicles
Allergic = distinct borders, vesicles/bullae, severe itching
Avoid triggers + use soap-free washes & emollients
Topical steroids (betamethasone 0.05%) = 1st-line
Oral steroids if severe (short course, taper to prevent rebound)
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