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Cardiovascular
Blepharitis
Types:
Anterior: Affects eyelid margins/eyelashes (crusting/scales)
Posterior: Affects meibomian glands (blocked glands, foamy tears)
Associations: Staphylococcal infection, seborrhoea, rosacea, allergy
Treatment:
General:
Warm compress 2–4x daily
Eyelid hygiene (proprietary cleansers; avoid baby shampoo)
Lubricating eye drops
Anterior: Chloramphenicol 1% ointment OD (if bacterial)
Posterior:
Doxycycline 100 mg OD (4–8 weeks, reduce to 50 mg)
Topical azithromycin if severe (doxycycline contraindicated)
Firm eyelid massage (express blocked oils)
NB: Address underlying rosacea/seborrhoea to prevent recurrence
Complications: Keratitis, chalazion, dry eye syndrome
Blepharitis
Types
Anterior Blepharitis:
Inflammation at the eyelid margins and eyelashes (outer edge)
Can be staphylococcal (crusting, scales at lash base) or seborrhoeic (greasy scales)
Often presents with redness, irritation, and possible lash debris
Posterior Blepharitis:
Involves the meibomian glands (inner lid margin)
Gland dysfunction leads to blocked orifices and foamy tears
Commonly associated with rosacea or seborrhoeic dermatitis
Associations
Staphylococcal infection (commonly S. aureus)
Seborrhoea (e.g. scalp dandruff)
Rosacea (facial redness, telangiectasia, papulopustular lesions)
Allergy (chronic inflammatory response)
Treatment
General Measures
Warm Compresses: 2–4 times daily, 5–10 minutes each, helps soften crusts and improve meibomian gland flow
Eyelid Hygiene:
Use proprietary eyelid cleansers specifically formulated for blepharitis (e.g. lid scrubs)
Avoid baby shampoo (can irritate eyes and disrupt tear film)
Lubricating Eye Drops: Alleviate dryness and irritation
Anterior Blepharitis
Topical Antibiotic Ointment:
e.g. Chloramphenicol 1% ointment once daily (HS) or BD if staphylococcal involvement is suspected
Apply to the lid margin, not just the conjunctival sac
Ensure concurrent lid hygiene to remove crusting
Posterior Blepharitis
Oral Doxycycline:
100 mg once daily for 4–8 weeks, then consider reducing to 50 mg daily
Monitor for GI side effects, consider sun protection due to photosensitivity
Topical Azithromycin (off-label or specialist recommended) if severe or doxycycline contraindicated
Firm Eyelid Massage: Gently express meibomian glands to improve lipid flow
Address underlying rosacea or seborrhoea (e.g. with topical metronidazole for facial rosacea, anti-seborrhoeic shampoos)
Complications
Keratitis: Corneal involvement can cause vision changes
Chalazion: Blocked meibomian gland cyst
Dry Eye Syndrome: Reduced tear film quality
Recurrent Infections: If poor lid hygiene persists
Notes
Blepharitis tends to be chronic and recurrent. Consistent lid hygiene is key to preventing flare-ups.
In rosacea-related blepharitis, controlling facial rosacea (topical or systemic therapies) helps reduce eyelid inflammation.
If severe pain, visual disturbance, or atypical presentation occurs, consider ophthalmology referral.
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