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Cardiovascular

Allergic Rhinitis


Risk Factors

  • Family history of atopy

  • Exposure to dust mites

  • Lack of exposure to animals in early life

  • Lack of older siblings

  • Non-attendance of childcare

  • Heavy maternal smoking in the first year of life

  • Early introduction of solid foods/formula


Note:

  • Urban living and environmental pollutants can exacerbate allergic rhinitis.

  • Strong association with comorbid asthma, eczema, and conjunctivitis (part of the atopic triad).


Pharm Treatment Ladder


1st Line:

  • Oral/intranasal antihistamines:

    • Loratadine 10 mg PO OD

    • Azelastine 125 mcg nasal spray, 1 spray BD

  • ADD intranasal steroids OR montelukast:

    • Mometasone 50 mcg, 2 sprays daily


2nd Line:

  • Montelukast 10 mg daily (5 mg for <14 yrs, 4 mg for <6 yrs)

    • ADD both intranasal steroid AND montelukast


For Rhinorrhoea:

  • Ipratropium 22 mcg/spray, 4 sprays TDS


If above fails:

  • Consider referral for immunotherapy

  • Review diagnosis and adherence


Note:

  • Intranasal saline irrigation can improve symptom control and reduce reliance on medications.

  • Sublingual immunotherapy (SLIT) may be a better option for patients unable to access allergen-specific immunotherapy.


Additonal Notes:

  • If allergic rhinitis + asthma, intranasal steroids are 1st line.

  • Be cautious with montelukast: potential for nightmares, aggression, and depression, which is reversible post-cessation.

  • Regular re-evaluation of treatment efficacy and compliance is essential for long-term management.

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