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Cardiovascular

Complex Regional Pain Syndrome (CRPS)



History

  • Post-injury or surgery (even minor trauma)

  • Severe distal limb pain, disproportionate to event

  • Early signs of disuse, functional decline


Diagnosis (Budapest Criteria)

Requires symptoms in ≥3 of 4 categories & signs in ≥1 category:


  • Sensory: Spontaneous pain, burning, hyperalgesia, allodynia

  • Vasomotor: Temperature asymmetry, skin colour changes (red, blue, pale)

  • Sudomotor/Oedema: Oedema, asymmetrical sweating

  • Motor/Trophic: Weakness, tremors, ↓ movement, hair/skin/nail changes


Additional Findings: ↓ ROM, pain with light touch


Management

  • Early physiotherapy (graded exercise, functional restoration)

  • Psychological support (CBT) for pain-related distress

  • Neuropathic pain management: Pregabalin/Gabapentin

  • Pain clinic referral (consider sympathetic nerve blocks)

  • Patient education: Early mobilisation, trigger avoidance

  • Adjuncts (less evidence): Opioids, corticosteroids, carbamazepine

  • Regular follow-up (monitor & adjust treatment)

  • Refractory cases: Mirror therapy

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