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Cardiovascular

Congestive Cardiac Failure (CCF)


Acute Pulmonary Oedema (APO) vs Decompensated CCF


Definition

  • APO: Medical emergency with rapid onset of severe breathlessness, widespread lung crackles, and hypoxia

  • Decompensated CCF: Gradual worsening of symptoms (sx) over days to weeks, often presenting with bilateral crackles and increased breathlessness


Initial Management of APO

  • Sit patient upright

  • Urgent ambulance transfer to ED with IV access using a large-bore cannula

  • Medications:

    • Furosemide: 20mg IV bolus or 40mg PO, repeat after 20 mins if no response

    • GTN: 400 mcg sublingual (up to 3 doses)

    • Morphine: 2.5mg IV slow bolus for symptomatic relief

  • Monitoring: Continuous ECG, BP, O2 saturations (aim >94%)

  • Consider IDC for urine monitoring if indicated


Management of Decompensated CCF


  • Outpatient management may be appropriate if clinically stable.

  • Diuretics: Increase current diuretic dose or start furosemide 20-40mg PO daily

  • Fluid Restriction: Limit to 1.5L/day if symptomatic with fluid overload

  • Follow-Up: Review within 24–48 hours; repeat CXR if required


Types of Heart Failure


Based on EF:

  • HFrEF: EF <40% (systolic dysfunction)

  • HFpEF: EF >50% (diastolic dysfunction)


Based on Ventricular Dysfunction:

  • Right-sided HF: Peripheral oedema, elevated JVP, hepatomegaly

  • Left-sided HF: Pulmonary congestion, SOB, bilateral crackles


Investigations

  • Bedside: ECG, BP, O2 sats, urine output (use IDC if severe)

  • Bloods: FBC, UECs, LFTs, TFTs, BNP, troponin (if ?ACS)

  • Imaging:

    • CXR: Pulmonary congestion, cardiomegaly, pleural effusions

    • Echo: Assess EF%, structural abnormalities (e.g., valves)

  • Other: Coronary angiography if ischaemia suspected


Complications

  • Pulmonary oedema

  • Renal impairment (due to diuretics, low output, cardiorenal syndrome)

  • Arrhythmias - AF, VT, sudden cardiac death

  • Hepatic congestion → chronic liver disease

  • Malnutrition and cachexia


Prognosis

  • Dependent on NYHA class and EF%

    • NYHA I: Mild sx → IV: Severe sx at rest

  • Median survival for HFrEF: ~5 years

Guidelines for Diuretics and Fluid Restriction

  • Diuretics: Start furosemide 20–40mg PO daily and titrate as needed. IV therapy for severe APO or acute decompensation

  • Fluid restriction: 1.5–2 L daily if symptomatic with fluid overload


Indications for Inotropes and Mechanical Circulatory Support

  • Inotropes: Indicated in acute decompensated HF with cardiogenic shock (e.g., dobutamine)

  • Mechanical Circulatory Support: LVAD or intra-aortic balloon pump for severe cases or as a bridge to transplant


Vaccination Recommendations

  • Influenza Vaccine: Annually for all HF patients

  • Pneumococcal Vaccine: Every 5 years to prevent respiratory infections


Optimisation of Medications and Monitoring Renal Function

  • ACEis/ARBs: Start low, titrate to max tolerated dose. Monitor K+ and Cr

  • BBs: Bisoprolol, carvedilol for stable HF. Gradually titrate dose

  • Spironolactone: Add for EF <35%. Monitor K+ closely

  • SGLT2 Inhibitors: Emerging role in HFrEF regardless of diabetes status​​

  • Monitoring: Regular UECs and electrolytes (K+, Na+). Risk of hypokalaemia and AKI

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