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Cardiovascular
Glomus Tumour
Definition
Benign tumour from the glomus body, which regulates skin blood flow in response to temperature
Common sites: Nail bed, palm

Symptoms
Small (1–2 cm), reddish-blue, painful nodule
Exquisitely tender, worsened by temperature changes or pressure
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Diagnosis
Clinical diagnosis based on solitary painful nodule
Biopsy (if needed): Shows glomus cells around small blood vessels
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Management
Surgical excision is curative, with symptom resolution after complete removal
Glomus Tumour
Definition
A glomus tumour is a benign neoplasm arising from the glomus body, a specialised arteriovenous structure involved in thermoregulation (regulating skin blood flow in response to temperature). The most common sites include the subungual region (under the nail bed) of the fingers or toes, though they can also appear on the palm, wrist, or forearm.

Symptoms
Typically small (1–2 cm), bluish-red or reddish-purple nodule
Exquisite tenderness to touch or pressure (even slight pressure can cause severe pain)
Pain may be exacerbated by temperature changes (cold sensitivity)
Often located under the nail plate, leading to a purple discoloration visible through the nail
Diagnosis
Clinical Diagnosis:
Solitary, painful subungual or fingertip nodule
Pain characteristically disproportionate to lesion size (intense, sharp)
Love’s Pin Test: Pinpoint tenderness at a specific spot
Hildreth’s Test: Pain relief with tourniquet (transient)
Imaging:
MRI or ultrasound can help localise the lesion, particularly if subungual and not well visualised
Biopsy/Histopathology:
Optional if clinical certainty is high; definitive if uncertain
Shows a characteristic proliferation of glomus cells surrounding small blood vessels
Management
Surgical Excision
Complete removal is curative, typically providing immediate relief from pain
Subungual lesions require careful approach to avoid nail bed damage
Follow-Up
Usually minimal post-operative follow-up if completely excised
Monitor for recurrence if the lesion was not fully removed or if multiple lesions exist
Notes
Glomus tumours are rare but should be considered in patients with focal fingertip pain that is intense and unrelieved by typical analgesics.
Differential diagnoses include subungual exostosis, pyogenic granuloma, subungual melanoma, myxoid cyst.
In uncertain cases, referral for specialist imaging (MRI) or hand surgery evaluation may be warranted.
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